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Article

Targeted ribose methylation of RNA in vivo directed by tailored antisense RNA guides.

Nature - 24 Oct 1996

Cavaillé J, Nicoloso M, Bachellerie J P

Abstract excerpt

Eukaryotic ribosomal RNAs are post-transcriptionally modified by methylation at the ribose sugar of specific nucleotides. This takes place in the nucleolus and involves a family of small nucleolar RNAs (snoRNAs) with long regions (10-21 nucleotides) complementary to rRNA sequences spanning the methylation site--a complementary snoRNA is required for methylation at a specific site. Here we show that altering the...

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PMID: 8878486
DOI: 10.1038/383732a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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