Article
[Association between cytochrome P-450 enzyme gene polymorphisms and Parkinson's disease].
Zhonghua yi xue za zhi - 1 Aug 2000
Wang J, Liu Z, Chen B
Abstract excerpt
OBJECTIVE: To explore the association between cytochrome P-450 enzyme gene polymorphisms and Parkinson's disease (PD). METHODS: The polymorphisms of CYP1A1 and CYP2E1 gene were analyzed in 158 PD patients and 150 unrelated healthy controls with PCR-RFLP and ASA techniques. RESULTS: (1) Of the 46 patients with early-onset PD, the frequency of the m2 allele was significantly higher than that in their matched...
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