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Article

Repression of cathepsin E expression increases the risk of mammary carcinogenesis and links to poor prognosis in breast cancer.

Carcinogenesis - 1 Mar 2014

Kawakubo Tomoyo, Yasukochi Atsushi, Toyama Tatsuya, Takahashi Satoru, Okamoto Kuniaki, Tsukuba Takayuki, Nakamura Seiji, Ozaki Yasuhiko, Nishigaki Koichi, Yamashita Hiroko, Yamamoto Kenji

Abstract excerpt

Despite advances in detection and treatment for breast cancer (BC), recurrence and death rates remain unacceptably high. Therefore, more convenient diagnostic and prognostic methods still required to optimize treatments among the patients. Here, we report the clinical significance of the serum cathepsin E (CatE) activity as a novel prognostic marker for BC. Correlation analysis between the serum levels of CatE...

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PMID: 24242330
DOI: 10.1093/carcin/bgt373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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