Phenotypic and functional characteristics of in vivo-induced interleukin-12-activated killer cells.

doi:10.1016/0165-2478(95)02460-3

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Article

Phenotypic and functional characteristics of in vivo-induced interleukin-12-activated killer cells.

Immunology letters - 1 Dec 1995

Nishimura T, Watanabe K, Lee U, Yahata T, Kobayashi M, Herrmann S H, Habu S

Abstract excerpt

A single i.p. administration of IL-12 (2000 U/mouse) into the mice caused the elevation of serum IFN-gamma activity and the generation of killer cells which can lyse various kinds of tumor cells including both NK-sensitive and -resistant tumor cells. Such in vivo induced killer cells were not det...

Topics

Animals
Cell Transplantation
Hematopoietic Stem Cells
Interleukin-12
Killer Cells, Natural
Lymphoma
Mice
Mice, Inbred C57BL
Phenotype

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