Article
Functional and phenotypical characteristics of hepatic NK-like T cells in NK1.1-positive and -negative mouse strains.
European journal of immunology - 1 Jun 1999
Shinohara K, Ikarashi Y, Maruoka H, Miyata M, Sugimura T, Terada M, Wakasugi H
Abstract excerpt
We previously reported and partially characterized a unique monoclonal antibody (mAb), U5A2-13, which recognizes a T cell subset similar to NK1.1+ T cells, not only in NK1.1-positive mouse strains but also in NK1.1-negative strains. In NK1.1-positive C57BL/6 mice, U5A2-13+ TCRalphabeta+ cells produced abundant IL-4 as well as extremely high levels of IFN-gamma upon CD3 cross-linking, but this did not occur with...
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