Article
Functional and phenotypic analyses of interleukin 2-activated tumor-infiltrating lymphocytes.
Biotherapy (Dordrecht, Netherlands) - 1 Jan 1990
Yamaue H, Tanimura H, Tsunoda T, Iwahashi M, Tani M, Tamai M, Inoue M
Abstract excerpt
The tumor-infiltrating lymphocytes (TILs) were cultured with interleukin 2 (IL-2) to induce the activated killer cells possessing autologous tumor-killing activity, and analysed their cell surface phenotypes and assessed anti-tumor killing activity. Furthermore, the activated TILs were transferred into 7 patients adoptively resulting in complete remission in a patient with pancreatic cancer and partial remission...
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