Article
On the mode of action of intravesical bacillus Calmette-Guérin: in vitro characterization of BCG-activated killer cells.
Urological research - 1 Jan 1994
Böhle A, Thanhäuser A, Ulmer A J, Mattern T, Ernst M, Flad H D, Jocham D
Abstract excerpt
Previously we had shown that, upon activation with viable bacillus Calmette-Guérin (BCG), peripheral blood mononuclear cells (PBMNC) could be rendered cytotoxic against otherwise insensitive natural killer (NK)-resistant bladder cancer cell lines. This phenomenon had been termed the BCG-activated killer (BAK) cell phenomenon. By means of depletion and enrichment procedures of mononuclear cell subpopulations...
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