Article
On the mode of action of intravesical bacillus Calmette-Guérin: in vitro characterization of BCG-activated killer cells.
Urological research - 1 Jan 1994
Böhle A, Thanhäuser A, Ulmer A J, Mattern T, Ernst M, Flad H D, Jocham D
Abstract excerpt
Previously we had shown that, upon activation with viable bacillus Calmette-Guérin (BCG), peripheral blood mononuclear cells (PBMNC) could be rendered cytotoxic against otherwise insensitive natural killer (NK)-resistant bladder cancer cell lines. This phenomenon had been termed the BCG-activated...
Topics
- Administration, Intravesical
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- CD5 Antigens
- Humans
- Immunotherapy
- Interferon-gamma
- Killer Cells, Natural
- Monocytes
- Mycobacterium bovis
- Phenotype
- T-Lymphocytes, Cytotoxic
- Tumor Cells, Cultured