Article
Defective autologous mixed lymphocyte reaction (AMLR) and killer activity generated in the AMLR in cancer patients.
International journal of cancer - 22 Apr 1992
Iwahashi M, Tanimura H, Yamaue H, Tsunoda T, Tani M, Tamai M, Noguchi K, Hotta T
Abstract excerpt
The autologous mixed lymphocyte reaction (AMLR) and the killer activity generated in the AMLR (AMLR-killer) in the spleen and the peripheral blood of patients with gastric cancer were investigated. The AMLR in cancer patients was suppressed, especially in the spleen, compared to that seen in controls. There was no correlation between AMLR activity and the stage status of the cancer. The cytotoxic activity of...
Topics
- Adult
- Aged
- Aged, 80 and over
- Autoimmunity
- Flow Cytometry
- Humans
- Killer Cells, Natural
- Lymphocyte Culture Test, Mixed
- Middle Aged
- Phenotype
- Spleen