Article
Establishment of anaplastic thyroid carcinoma cell lines useful for analysis of chemosensitivity and carcinogenesis.
The Journal of clinical endocrinology and metabolism - 1 Oct 1996
Asakawa H, Kobayashi T, Komoike Y, Yanagawa T, Takahashi M, Wakasugi E, Maruyama H, Tamaki Y, Matsuzawa Y, Monden M
Abstract excerpt
Anaplastic thyroid carcinoma (ATC) is usually associated with a poor prognosis, with most patients dying within a few months. The mechanism of its carcinogenesis is unclear, and its rapid growth and spread often prevent effective surgical therapy. Thus, chemotherapy is necessary. However, ATC is often resistant to anticancer drugs. Therefore, prediction of chemosensitivity is important in selecting appropriate...
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