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Article

Role of caspase 8 as a determinant in chemosensitivity of p53-mutated head and neck squamous cell carcinoma cell lines.

Journal of medical and dental sciences - 1 Mar 2006

Kaneda Yoshimasa, Shimamoto Hiroaki, Matsumura Kouji, Arvind Ramanathan, Zhang Shengliang, Sakai Eiki, Omura Ken, Tsuchida Nobuo

Abstract excerpt

We studied factors that control chemoresistance to 6 head and neck squamous cell carcinoma cell lines carrying p53 mutations. Cell lines were chosen, based on the presence of EGFR amplifications, the presence of H-ras mutations, and the absence of either. WST-1 viability assays showed that, in response to etoposide, Ca922 was most sensitive, HOC313 most resistant, and HSC6 and the others moderately sensitive. A...

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PMID: 16722146

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EGFR
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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