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Article

Role of Krüppel-Like Factor 4 in the Maintenance of Chemoresistance of Anaplastic Thyroid Cancer.

Thyroid : official journal of the American Thyroid Association - 1 Nov 2017

Lee Su In, Kim Dae Kyoung, Seo Eun Jin, Choi Eun Jung, Kwon Yang Woo, Jang Il Ho, Lee Jin Choon, Kim Hyun Yul, Shong Minho, Kim Jae Ho, Kim Seong-Jang

Abstract excerpt

BACKGROUND: Anaplastic thyroid cancer (ATC) has a very poor prognosis due to its aggressive nature and resistance to conventional treatment. Radiotherapy and chemotherapy are not fully effective because of the undifferentiated phenotype and enhanced drug resistance of ATC. The objective of this study was to evaluate the involvement of Krüppel-like factor 4 (KLF4), a stemness-associated transcription factor, in...

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Source

Identifiers

PMID: 28920531
DOI: 10.1089/thy.2016.0414

Genes

KLF4
ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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