Article
Identification and characterization of a yeast gene encoding the U2 small nuclear ribonucleoprotein particle B" protein.
Molecular and cellular biology - 1 Jun 1996
Tang J, Abovich N, Rosbash M
Abstract excerpt
The inessential yeast gene MUD2 encodes a protein factor that contributes to U1 small nuclear ribonucleoprotein particle (snRNP)-pre-mRNA complex (commitment complex) formation. To identify other genes that contribute to this early splicing step, we performed a synthetic lethal screen with a MUD2 deletion strain. The first characterized gene from this screen, MSL1 (MUD synthetic lethal 1), encodes the yeast...
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