Article
No association found between Alzheimer's disease and a mitochondrial tRNA glutamine gene variant.
Neuroscience letters - 8 Dec 1995
Wragg M A, Talbot C J, Morris J C, Lendon C L, Goate A M
Abstract excerpt
We have screened a large sample of patients with sporadic late-onset dementia of the Alzheimer type (DAT) and age-matched controls for a mitochondrial tRNA(Gln) variant previously reported to be associated with increased risk of developing Alzheimer's disease (AD). The frequency of an Ava II site gain was determined by restriction analysis of a PCR-amplified mitochondrial DNA product. One of 155 DAT cases and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.