Mutations and infinity: improved statistical methods for estimating spontaneous rates.

doi:10.1002/(SICI)1098-2280(1996)28:2<90::AID-EM4>3.0.CO;2-I

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Article

Mutations and infinity: improved statistical methods for estimating spontaneous rates.

Environmental and molecular mutagenesis - 1 Jan 1996

Nádas A, Goncharova E I, Rossman T G

Abstract excerpt

Certain mathematical artifacts which had been appended by others to Luria and Delbrück's [Genetics 28: 491-511, 1943] model of spontaneous mutagenesis in bacterial populations have added confusion to the modeling and measurement of spontaneous mutation rates. Additional confusion arises when mode...

Topics

Cell Culture Techniques
Genetic Variation
Models, Genetic
Models, Statistical
Mutation

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