Article
Characterization of lipophosphoglycan from a ricin-resistant mutant of Leishmania major.
Glycobiology - 1 Jun 1996
Opat A, Ng K, Currie G, Handman E, Bacic A
Abstract excerpt
One of the virulence factors of the protozoan parasite Leishmania major is the surface glycoconjugate, lipophosphoglycan (LPG). A Ricin-resistant mutant of L.major was generated and characterised with respect to its virulence in mice and the structure and expression of LPG. The LPG from this mutant (1F6-B5) retained the tripartite structure of wild-type LPG, comprising a glycosylphosphatidylinositol (GPI) anchor...
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