Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of lipophosphoglycan from a ricin-resistant mutant of Leishmania major.

Glycobiology - 1 Jun 1996

Opat A, Ng K, Currie G, Handman E, Bacic A

Abstract excerpt

One of the virulence factors of the protozoan parasite Leishmania major is the surface glycoconjugate, lipophosphoglycan (LPG). A Ricin-resistant mutant of L.major was generated and characterised with respect to its virulence in mice and the structure and expression of LPG. The LPG from this muta...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbohydrate Sequence
Share to Chromatography, High Pressure Liquid
Share to Drug Resistance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to Mice, Inbred C3H

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 8842702
DOI: 10.1093/glycob/6.4.387

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8842702-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of lipophosphoglycan from a ricin-resistant mutant of Leishmania major.PMID 8842702Read ↗

Lipophosphoglycan expression and virulence in ricin-resistant variants of Leishmania major.Semantic proximity Read ↗

Isolation of virulence genes directing surface glycosyl-phosphatidylinositol synthesis by functional complementation of Leishmania.Semantic proximity Read ↗

Leishmania LPG3 encodes a GRP94 homolog required for phosphoglycan synthesis implicated in parasite virulence but not viability.Semantic proximity Read ↗

Regulated expression of the <i>Leishmania major</i> surface virulence factor lipophosphoglycan using conditionally destabilized fusion proteinsSemantic proximity Read ↗

Phosphoglycan Repeat-deficient Leishmania mexicana Parasites Remain Infectious to Macrophages and MiceSemantic proximity Read ↗

Glycosylation defects and virulence phenotypes of Leishmania mexicana phosphomannomutase and dolicholphosphate-mannose synthase gene deletion mutants.Semantic proximity Read ↗

Characterization of a Leishmania mexicana mutant defective in synthesis of free and protein-linked GPI glycolipids.Semantic proximity Read ↗

Comparisons of mutants lacking the Golgi UDP-galactose or GDP-mannose transporters establish that phosphoglycans are important for promastigote but not amastigote virulence in Leishmania major.Semantic proximity Read ↗

Persistence without pathology in phosphoglycan-deficient Leishmania major.Semantic proximity Read ↗

Molecular variation in Leishmania.Semantic proximity Read ↗

Defective galactofuranose addition in lipophosphoglycan biosynthesis in a mutant of Leishmania donovani.Semantic proximity Read ↗

The role(s) of lipophosphoglycan (LPG) in the establishment of Leishmania major infections in mammalian hosts.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.