Lipophosphoglycan expression and virulence in ricin-resistant variants of Leishmania major.

doi:10.1016/0166-6851(90)90047-p

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Article

Lipophosphoglycan expression and virulence in ricin-resistant variants of Leishmania major.

Molecular and biochemical parasitology - 1 May 1990

Elhay M, Kelleher M, Bacic A, McConville M J, Tolson D L, Pearson T W, Handman E

Abstract excerpt

Lipophosphoglycan (LPG) of Leishmania is a polymorphic molecule comprising an alkylglycerol anchor, a conserved oligosaccharide core and a species-specific polymer of oligosaccharide repeats jointed by phosphodiester bonds. This molecule, together with the membrane polypeptide gp63, has been impl...

Topics

Animals
Antibodies, Monoclonal
Drug Resistance
Genetic Variation
Glycosphingolipids
Leishmania tropica
Leishmaniasis
Mice
Mice, Inbred BALB C
Ricin
Virulence

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