Article
Multicopy suppressors of temperature-sensitive mutations of yeast mRNA capping enzyme.
Gene expression - 1 Jan 1996
Schwer B, Shuman S
Abstract excerpt
We have isolated three Saccharomyces cerevisiae genes-CES1, CES2, and CES3-- that, when present in high copy, suppress the ts growth defect caused by mutations in the CEG1 gene encoding mRNA guanylyltransferase (capping enzyme). Molecular characterization of the capping enzyme suppressor genes re...
Topics
- Amino Acid Sequence
- Cloning, Molecular
- DNA Mutational Analysis
- Fungal Proteins
- Genes, Fungal
- Genes, Suppressor
- Guanine Nucleotide Exchange Factors
- Molecular Sequence Data
- Mutation
- Nucleotidyltransferases
- Restriction Mapping
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Amino Acid
- Temperature
- Vaccinia virus
- mRNA Guanylyltransferases