Article
The Peptide Repertoire of HLA-B27 may include Ligands with Lysine at P2 Anchor Position.
Proteomics - 1 May 2018
Yair-Sabag Shira, Tedeschi Valentina, Vitulano Carolina, Barnea Eilon, Glaser Fabian, Melamed Kadosh Dganit, Taurog Joel D, Fiorillo Maria Teresa, Sorrentino Rosa, Admon Arie
Abstract excerpt
The HLA-B*27 peptidome has drawn significant attention due to the genetic association between some of the HLA-B*27 alleles and the inflammatory rheumatic disease ankylosing spondylitis (AS), for which a comprehensive biological explanation is still lacking. This study aims to expand the known limits of the HLA-B*27 peptidome to facilitate selection and testing of new peptides, possibly involved in the disease....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
