Article
The mouse lysosomal membrane protein 1 gene as a candidate for the motorneuron degeneration (mnd) locus.
Genomics - 1 Mar 1996
Bermingham N A, Martin J E, Fisher E M
Abstract excerpt
The motorneuron degeneration (mnd) mutation causes one of the few late-onset progressive neurodegenerations in mice; therefore, the mnd mouse is a valuable paradigm for studying neurodegenerative biology. The mnd mutation may also model human neuronal ceroid lipofuscinosis (NCL) or Batten disease. mnd maps to the centromeric region of mouse chromosome 8, which likely corresponds to portions of human chromosomes...
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