Article
The major brain isoform of kif1b lacks the putative mitochondria-binding domain.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 1999
Conforti L, Buckmaster E A, Tarlton A, Brown M C, Lyon M F, Perry V H, Coleman M P
Abstract excerpt
Kinesin and kinesin superfamily proteins are molecular motors involved in important intracellular functions such as organelle transport and cell division. They are microtubule-activated ATPases composed of a motor domain that binds to microtubules and a cargo-binding domain that binds to specific organelles. While searching for the slow Wallerian degeneration mutation (WldS) on distal mouse Chromosome (Chr) 4, we...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Binding Sites
- Brain
- Chromosome Mapping
- Cloning, Molecular
- DNA Mutational Analysis
- Kinesins
- Mice
- Mice, Inbred C57BL