Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retinal degeneration in motor neuron degeneration: a mouse model of ceroid lipofuscinosis.

Investigative ophthalmology & visual science - 1 Mar 1994

Chang B, Bronson R T, Hawes N L, Roderick T H, Peng C, Hageman G S, Heckenlively J R

Abstract excerpt

PURPOSE: To evaluate the retinal degeneration of the motor neuron degeneration (mnd) mouse, and to confirm its inheritance pattern and gene location. METHODS: In screening the mnd/mnd mouse for ocular disease, a retinal degeneration was found that was evaluated by serial electroretinography, histology, electron microscopy, indirect ophthalmoscopy, and genetic and linkage analysis. RESULTS: In homozygous mnd mice,...

Topics

Alleles
Animals
Electroretinography
Female
Genetic Linkage
Male
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Mutant Strains
Motor Neurons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nerve Degeneration

Neuronal Ceroid-Lipofuscinoses

Photoreceptor Cells

Retina

Retinal Degeneration

Source

Identifiers

PMID: 8125718

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8125718-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retinal degeneration in motor neuron degeneration: a mouse model of ceroid lipofuscinosis.PMID 8125718Read ↗

Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA).Semantic proximity Read ↗

An early-onset congenic strain of the motor neuron degeneration (mnd) mouse.Semantic proximity Read ↗

A New Cerkl Mouse Model Generated by CRISPR-Cas9 Shows Progressive Retinal Degeneration and Altered Morphological and Electrophysiological Phenotype.Semantic proximity Read ↗

Phenotypic characterization of a mouse model of juvenile neuronal ceroid lipofuscinosis.Semantic proximity Read ↗

Retinal pathology and function in a Cln3 knockout mouse model of juvenile Neuronal Ceroid Lipofuscinosis (batten disease).Semantic proximity Read ↗

New mouse primary retinal degeneration (rd-3).Semantic proximity Read ↗

Cerebellar defects in a mouse model of juvenile neuronal ceroid lipofuscinosisSemantic proximity Read ↗

Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9Semantic proximity Read ↗

Retinal degeneration 6 (rd6): a new mouse model for human retinitis punctata albescens.Semantic proximity Read ↗

Mouse Models as Tools to Identify Genetic Pathways for Retinal Degeneration, as Exemplified by Leber's Congenital Amaurosis.Semantic proximity Read ↗

Visual deficits in a mouse model of Batten disease are the result of optic nerve degeneration and loss of dorsal lateral geniculate thalamic neurons.Semantic proximity Read ↗

Gene Therapy Targeting the Inner Retina Rescues the Retinal Phenotype in a Mouse Model of CLN3 Batten Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.