Article
Retinal degeneration in motor neuron degeneration: a mouse model of ceroid lipofuscinosis.
Investigative ophthalmology & visual science - 1 Mar 1994
Chang B, Bronson R T, Hawes N L, Roderick T H, Peng C, Hageman G S, Heckenlively J R
Abstract excerpt
PURPOSE: To evaluate the retinal degeneration of the motor neuron degeneration (mnd) mouse, and to confirm its inheritance pattern and gene location. METHODS: In screening the mnd/mnd mouse for ocular disease, a retinal degeneration was found that was evaluated by serial electroretinography, histology, electron microscopy, indirect ophthalmoscopy, and genetic and linkage analysis. RESULTS: In homozygous mnd mice,...
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