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Article

Dlg5 maintains apical polarity by promoting membrane localization of Crumbs during Drosophila oogenesis.

Scientific reports - 23 May 2016

Luo Jun, Wang Heng, Kang Di, Guo Xuan, Wan Ping, Wang Dou, Chen Jiong

Abstract excerpt

Apical-basal polarity plays critical roles in the functions of epithelial tissues. However, the mechanisms of epithelial polarity establishment and maintenance remain to be fully elucidated. Here we show that the membrane-associated guanylate kinase (MAGUK) family protein Dlg5 is required for the maintenance of apical polarity of follicle epithelium during Drosophila oogenesis. Dlg5 localizes at the apical...

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Identifiers

PMID: 27211898
DOI: 10.1038/srep26553
PMCID: PMC4876392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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