Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A closely linked gene to apolipoprotein E may serve as an additional risk factor for Alzheimer's disease.

Neuroscience letters - 1 Dec 1995

Poduslo S E, Neal M, Schwankhaus J

Abstract excerpt

The E4 allele of the apolipoprotein E (APOE) gene has been identified as a risk factor for Alzheimer's disease. Immediately downstream from the APOE gene on chromosome 19 is the gene for apolipoprotein CI (APOCI). We have found that the frequency of an APOCI restriction site is 0.45 for Alzheimer's patients and 0.14 for control spouses, which is similar to the frequencies for the APOE4 allele. The APOE4 allele is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Phenotype

Share to Restriction Mapping

Share to Risk Factors

Source

Identifiers

PMID: 8830319
DOI: 10.1016/0304-3940(95)12158-z

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

A closely linked gene to apolipoprotein E may serve as an additional risk factor for Alzheimer's disease.PMID 8830319Read ↗

The apolipoprotein CI A allele as a risk factor for Alzheimer's disease.Semantic proximity Read ↗

Genetic association and linkage analysis of the apolipoprotein CII locus and familial Alzheimer's disease.Semantic proximity Read ↗

A new locus on chromosome 19 linked with late-onset Alzheimer's disease.Semantic proximity Read ↗

The apolipoprotein E/CI/CII gene cluster and late-onset Alzheimer disease.Semantic proximity Read ↗

Linkage of late-onset Alzheimer's disease with apolipoprotein E type 4 on chromosome 19Semantic proximity Read ↗

Apolipoprotein E alleles but neither apolipoprotein B nor apolipoprotein AI/CIII alleles are associated with late onset, familial Alzheimer's disease.Semantic proximity Read ↗

Confirmation of association between the e4 allele of apolipoprotein E and Alzheimer's disease.Semantic proximity Read ↗

Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13?Semantic proximity Read ↗

Apo E and Apo CI loci are associated with dementia in younger but not older late-onset cases.Semantic proximity Read ↗

Further analysis of previously implicated linkage regions for Alzheimer's disease in affected relative pairs.Semantic proximity Read ↗

Are the associations between Alzheimer's disease and polymorphisms in the apolipoprotein E and the apolipoprotein CII genes due to linkage disequilibrium?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.