Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apo E and Apo CI loci are associated with dementia in younger but not older late-onset cases.

Dementia and geriatric cognitive disorders - 1 Jan 2000

Tysoe C, Galinsky D, Robinson D, Brayne C, Huppert F A, Dening T, Paykel E S, Easton D F, Rubinsztein D C

Abstract excerpt

Numerous groups have confirmed that apolipoprotein E allelic variation accounts for a proportion of the genetic risk for late-onset Alzheimer's disease (AD). However, there is a paucity of data on the impact of this locus on the overall risk of dementia (as opposed to AD) in the elderly. Most studies have ascertained specifically AD cases from hospital clinics or brain banks and many demented cases have vascular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Alleles

Share to Genotype

Share to Haplotypes

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 9681640
DOI: 10.1159/000017046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Apo E and Apo CI loci are associated with dementia in younger but not older late-onset cases.PMID 9681640Read ↗

Analysis of alpha-1 antichymotrypsin, presenilin-1, angiotensin-converting enzyme, and methylenetetrahydrofolate reductase loci as candidates for dementia.Semantic proximity Read ↗

Apolipoprotein E alleles but neither apolipoprotein B nor apolipoprotein AI/CIII alleles are associated with late onset, familial Alzheimer's disease.Semantic proximity Read ↗

The apolipoprotein CI A allele as a risk factor for Alzheimer's disease.Semantic proximity Read ↗

The apolipoprotein E/CI/CII gene cluster and late-onset Alzheimer disease.Semantic proximity Read ↗

Apolipoprotein E genotype and major depression in a community of older adults. The Cache County Study.Semantic proximity Read ↗

Apolipoprotein E genotype and association between smoking and early onset Alzheimer's disease.Semantic proximity Read ↗

Genetic association and linkage analysis of the apolipoprotein CII locus and familial Alzheimer's disease.Semantic proximity Read ↗

A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping or DNA sequencing. V. Analysis of case/control sampling designs: Alzheimer's disease and the apoprotein E locus.Semantic proximity Read ↗

A closely linked gene to apolipoprotein E may serve as an additional risk factor for Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.