Article
The role of HIV type 1 phenotype and genotype in long-term responders to zidovudine therapy.
AIDS research and human retroviruses - 20 Jul 1996
Angarano G, Monno L, Vivirito M C, Appice A, Romanelli C, Giannelli A, La Grasta L, Fracasso C, Fiore J R, Milazzo F
Abstract excerpt
We performed a cross-sectional and partly retrospective virological evaluation of 31 long-term responders (LTRs) to zidovudine (ZDV) (persistent increase in the CD4+ cell counts without progression of HIV infection throughout a period of ZDV therapy > 3 years) and 17 well-matched controls who dev...
Topics
- Acquired Immunodeficiency Syndrome
- CD4 Lymphocyte Count
- Cohort Studies
- Cross-Sectional Studies
- Drug Resistance, Microbial
- Female
- Genotype
- HIV-1
- Humans
- Italy
- Male
- Mutagenesis
- Phenotype
- Polymerase Chain Reaction
- Prognosis
- Retrospective Studies
- Survivors
- Zidovudine