Article
Viral phenotype and T cell reactivity in human immunodeficiency virus type 1-infected asymptomatic men treated with zidovudine.
The Journal of infectious diseases - 1 Sept 1993
Koot M, Schellekens P T, Mulder J W, Lange J M, Roos M T, Coutinho R A, Tersmette M, Miedema F
Abstract excerpt
The effect of zidovudine on disease progression in asymptomatic human immunodeficiency virus type 1 (HIV-1)-infected men (n = 52) in relation to CD4 T cell numbers, T cell reactivity, and HIV-1 biologic phenotype was studied in a double-blind randomized trial over 2 years. CD4+ cell numbers and T cell reactivity did not differ significantly between the zidovudine- and placebo-treated groups, except for a...
Topics
- Acquired Immunodeficiency Syndrome
- CD4-Positive T-Lymphocytes
- Double-Blind Method
- Genetic Variation
- HIV Infections
- HIV Seropositivity
- HIV-1
- Homosexuality
- Humans
- Male