Article
Viral phenotype, antiretroviral resistance and clinical evolution in human immunodeficiency virus-infected children.
The Pediatric infectious disease journal - 1 Nov 1997
Mellado M J, Cilleruelo M J, Ortiz M, Villota J, García M, Perez-Jurado M L, Barreiro G, Martín-Fontelos P, Bernal A
Abstract excerpt
BACKGROUND: The syncytium-inducing (SI) viral phenotype and the emergence of viral strains resistant to zidovudine have been described in persons infected with HIV, and in some cases they have been associated with poor prognosis. METHODS: HIV isolates obtained from 37 HIV-infected children were analyzed to determine whether the SI viral phenotype and the mutation on the 215 position of the reverse transcriptase...
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