Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pathogenicity and diversity of HIV and implications for clinical management: a review.

Journal of acquired immune deficiency syndromes - 1 Jan 1994

Saag M S, Hammer S M, Lange J M

Abstract excerpt

Genetic variation of human immunodeficiency virus (HIV) over time is an important consideration in long-term antiretroviral therapy, in all likelihood affecting the course of HIV disease and its response to antiretroviral therapy. Viral replication persists throughout HIV disease, and viral burden is correlated with disease stage. CD4+ T-helper cells, a prime target for HIV, appear responsible for direct cellular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to CD4-Positive T-Lymphocytes
Share to Cytokines

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Microbial

Share to Genetic Variation

Share to Genotype

Share to HIV Infections

Share to Phenotype

Source

Identifiers

PMID: 7965648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pathogenicity and diversity of HIV and implications for clinical management: a review.PMID 7965648Read ↗

The origin and diversity of the HIV-1 pandemic.Semantic proximity Read ↗

Using HIV-1 sequence variability to explore virus biology.Semantic proximity Read ↗

Implications of HIV diversity for the HIV-1 pandemic.Semantic proximity Read ↗

Diversity and variation in human immunodeficiency virus: implications for immune control.Semantic proximity Read ↗

HIV genetic diversity: biological and public health consequences.Semantic proximity Read ↗

Molecular epidemiology of HIV-1 variants in the global AIDS pandemic: an update.Semantic proximity Read ↗

Derivation and Characterization of Pathogenic Transmitted/Founder Molecular Clones from Simian Immunodeficiency Virus SIVsmE660 and SIVmac251 following Mucosal Infection.Semantic proximity Read ↗

The clades of HIV: their origins and clinical significance.Semantic proximity Read ↗

HIV-1 biological phenotype varies with severity of infection across HIV-1 genetic subtypes.Semantic proximity Read ↗

The emerging genetic diversity of HIV. The importance of global surveillance for diagnostics, research, and prevention.Semantic proximity Read ↗

Conversion rate towards a syncytium-inducing (SI) phenotype during different stages of human immunodeficiency virus type 1 infection and prognostic value of SI phenotype for survival after AIDS diagnosis.Semantic proximity Read ↗

Molecular determinants of human immunodeficiency virus type I phenotype variability.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.