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Article

Host genotype controls the ability of the ISGF3 complex to activate transcription of IFN-inducible genes.

Journal of cellular biochemistry - 1 Jan 1996

Gariglio M, Foresta P, Ying G G, Gaboli M, Lembo D, Landolfo S

Abstract excerpt

C57BL/6 mice are unable to express the Ifi 202 type genes upon injection in vivo of multiple dsRNA, poly rl:rC, or IFN-treatment in vitro. For this purpose the 5' terminal flanking region (called the b segment of 804 bp) was linked to a heterologous reporter gene chloramphenicol acetyl transferase (CAT) and transfected into NIH3T3 cells or BLK cells derived from the C57BL/6 strain. IFN-alpha induced strong CAT...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 8825418
DOI: 10.1002/(SICI)1097-4644(19960101)60:1%3C83::AID-JCB11%3E3.0.CO;2-L

Genes

CAT
BLK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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