Host genotype controls the ability of the ISGF3 complex to activate transcription of IFN-inducible genes.

doi:10.1002/(SICI)1097-4644(19960101)60:1%3C83::AID-JCB11%3E3.0.CO;2-L

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Article

Host genotype controls the ability of the ISGF3 complex to activate transcription of IFN-inducible genes.

Journal of cellular biochemistry - 1 Jan 1996

Gariglio M, Foresta P, Ying G G, Gaboli M, Lembo D, Landolfo S

Abstract excerpt

C57BL/6 mice are unable to express the Ifi 202 type genes upon injection in vivo of multiple dsRNA, poly rl:rC, or IFN-treatment in vitro. For this purpose the 5' terminal flanking region (called the b segment of 804 bp) was linked to a heterologous reporter gene chloramphenicol acetyl transferas...

Topics

3T3 Cells
Animals
Base Sequence
Chloramphenicol O-Acetyltransferase
DNA-Binding Proteins
Female
Genes, Reporter
Genotype
Interferon-Stimulated Gene Factor 3
Interferon-Stimulated Gene Factor 3, gamma Subunit
Interferon-alpha
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Oligonucleotide Probes
Promoter Regions, Genetic
RNA, Messenger
Transcription Factors

Source

Open in PubMed

Identifiers

PMID: 8825418
DOI: 10.1002/(SICI)1097-4644(19960101)60:1%3C83::AID-JCB11%3E3.0.CO;2-L

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8825418-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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