Article
Characterization of nuclear factors involved in 202 gene induction by interferon-alpha in murine leukemia cells.
European journal of biochemistry - 15 Apr 1994
Gariglio M, Gaboli M, Mana C, Ying G G, Gribaudo G, Cavallo R, Landolfo S
Abstract excerpt
The 5' terminal flanking region of the interferon-inducible gene, 202, contains an interferon-stimulable response element (ISRE), called a GA box, that confers inducibility by interferon(IFN)-alpha, but not by IFN-gamma, on a reporter gene, such as the chloramphenicol acetyltransferase (CAT). Nuclear extracts from L1210 murine leukemia cells, stimulated for various periods of time with IFN-alpha, were mixed with...
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