An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo.

doi:10.1016/0092-8674(95)90292-9

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Article

An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo.

Cell - 24 Mar 1995

Ruberte E, Marty T, Nellen D, Affolter M, Basler K

Abstract excerpt

TGF beta elicits diverse cellular responses by signaling through receptor complexes formed by two distantly related transmembrane serine/threonine kinases called type II and type I receptors. Previous studies have indicated that the product of the Drosophila thick veins (tkv) gene is a type I rec...

Topics

Activin Receptors
Alleles
Animals
Animals, Genetically Modified
Drosophila
Drosophila Proteins
Embryo, Nonmammalian
Genes, Insect
Homozygote
Insect Hormones
Molecular Sequence Data
Protein Serine-Threonine Kinases
Receptors, Cell Surface
Receptors, Growth Factor
Signal Transduction
Transcription, Genetic
Transforming Growth Factor beta
Vertebrates

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Identifiers

PMID: 7697719
DOI: 10.1016/0092-8674(95)90292-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7697719-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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