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Article

An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo.

Cell - 24 Mar 1995

Ruberte E, Marty T, Nellen D, Affolter M, Basler K

Abstract excerpt

TGF beta elicits diverse cellular responses by signaling through receptor complexes formed by two distantly related transmembrane serine/threonine kinases called type II and type I receptors. Previous studies have indicated that the product of the Drosophila thick veins (tkv) gene is a type I receptor for decapentaplegic (dpp). Here, we show that the Drosophila gene punt encodes a homolog of a vertebrate type II...

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PMID: 7697719
DOI: 10.1016/0092-8674(95)90292-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo.PMID 7697719Read ↗

Genetic analysis of punt, a type II Dpp receptor that functions throughout the Drosophila melanogaster life cycle.Semantic proximity Read ↗

Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF beta homologs during Drosophila embryogenesis.Semantic proximity Read ↗

Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic.Semantic proximity Read ↗

Characterization and relationship of Dpp receptors encoded by the saxophone and thick veins genes in Drosophila.Semantic proximity Read ↗

Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing.Semantic proximity Read ↗

Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins.Semantic proximity Read ↗

A genetic screen for modifiers of Drosophila decapentaplegic signaling identifies mutations in punt, Mothers against dpp and the BMP-7 homologue, 60A.Semantic proximity Read ↗

Schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1.Semantic proximity Read ↗

The Drosophila decapentaplegic and short gastrulation genes function antagonistically during adult wing vein development.Semantic proximity Read ↗

The Drosophila saxophone gene: a serine-threonine kinase receptor of the TGF-beta superfamily.Semantic proximity Read ↗

Drosophila p24 homologues eclair and baiser are necessary for the activity of the maternally expressed Tkv receptor during early embryogenesis.Semantic proximity Read ↗

The Drosophila schnurri gene acts in the Dpp/TGF beta signaling pathway and encodes a transcription factor homologous to the human MBP family.Semantic proximity Read ↗

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