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Article

New negative feedback regulators of Egfr signaling in Drosophila.

Genetics - 1 Aug 2012

Butchar Jonathan P, Cain Donna, Manivannan Sathiya N, McCue Andrea D, Bonanno Liana, Halula Sarah, Truesdell Sharon, Austin Christina L, Jacobsen Thomas L, Simcox Amanda

Abstract excerpt

The highly conserved epidermal growth factor receptor (Egfr) pathway is required in all animals for normal development and homeostasis; consequently, aberrant Egfr signaling is implicated in a number of diseases. Genetic analysis of Drosophila melanogaster Egfr has contributed significantly to understanding this conserved pathway and led to the discovery of new components and targets. Here we used microarray...

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Identifiers

PMID: 22595244
DOI: 10.1534/genetics.112.141093
PMCID: PMC3416002

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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