Article
Truncations of the C-terminus have different effects on the conformation and activity of phosphatidylinositol transfer protein.
Biochemistry - 24 Sept 1996
Voziyan P A, Tremblay J M, Yarbrough L R, Helmkamp G M
Abstract excerpt
Contributions of the C-terminus toward the conformation and activity of phosphatidylinositol transfer protein (PITP) were studied by comparing properties of the 271 amino acid, full-length protein, PITP(1-271), and two truncated species, PITP(1-259) and PITP(1-253). Using recombinant proteins and an in vitro phospholipid transfer assay with phosphatidylcholine vesicles, the activities of PITP(1-271) and...
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