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Article

Characterization of the C-terminal ER membrane anchor of PTP1B.

Experimental cell research - 10 Sept 2007

Anderie Ines, Schulz Irene, Schmid Andreas

Abstract excerpt

The tyrosine phosphatase PTP1B is an important regulator of cell function. In living cells PTP1B activity is restricted to the vicinity of the endoplasmic reticulum (ER) by post-translational C-terminal attachment of PTP1B to the ER membrane network. In our study we investigated the membrane anchor of PTP1B by use of EGFP fusion proteins. We demonstrate that the membrane anchor of PTP1B cannot be narrowed down to...

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Identifiers

PMID: 17643420
DOI: 10.1016/j.yexcr.2007.05.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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