Article
A complex neutralization domain of bluetongue virus serotype 17 defines a virulence-associated marker.
Viral immunology - 1 Jan 1996
Bernard K A, Israel B A, Schultz K T
Abstract excerpt
A panel of seven monoclonal antibodies (MAb) was used to characterize a virulence-associated marker on bluetongue virus serotype 17 (BLU-17). These MAbs poorly neutralize virulent BLU-17 isolates, but effectively neutralize avirulent isolates (2). The MAbs immunoprecipitated VP2, an outer capsid protein, of both virulent and avirulent BLU-17 isolates despite their failure to neutralize the virulent isolates. The...
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