Article
Impaired uptake and/or utilization of leucine by Saccharomyces cerevisiae is suppressed by the SPT15-300 allele of the TATA-binding protein gene.
Applied and environmental microbiology - 1 Oct 2009
Baerends Richard J S, Qiu Jin-Long, Rasmussen Simon, Nielsen Henrik Bjørn, Brandt Anders
Abstract excerpt
Successful fermentations to produce ethanol require microbial strains that have a high tolerance to glucose and ethanol. Enhanced glucose/ethanol tolerance of the laboratory yeast Saccharomyces cerevisiae strain BY4741 under certain growth conditions as a consequence of the expression of a dominant mutant allele of the SPT15 gene (SPT15-300) corresponding to the three amino acid changes F177S, Y195H, and K218R...
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