Article
Disruption of RIM15 confers an increased tolerance to heavy metals in Saccharomyces cerevisiae.
Biotechnology letters - 1 Jul 2020
Kim Hyun-Soo
Abstract excerpt
OBJECTIVE: The aim of this study was to identify genes related to a heavy metal tolerance and to elucidate the tolerance mechanism in a eukaryote model using Saccharomyces cerevisiae. RESULTS: In this study, one strain tolerant to up to 50 μM Pb(NO3)2 and 30 μM CdCl2 was isolated by screening a transposon-mediated mutant library and the disrupted gene was determined to be RIM15. In addition, this gene's...
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