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Article

Phenotypic manifestations of insulin-like growth factor binding protein-1 (IGFBP-1) and IGFBP-3 overexpression in transgenic mice.

Progress in growth factor research - 1 Jan 1995

Murphy L J, Rajkumar K, Molnar P

Abstract excerpt

To provide further insight into the function of the IGFBPs, transgenic (Tg) mice which overexpressed IGFBP-1 and IGFBP-3 were generated. In this report we have compared the phenotypic manifestations observed in these Tg mice. The IGFBP-1 Tg mice were significantly smaller at birth, birth weight and gained less weight in the postnatal period. Organ weight was proportionately reduced relative to body weight in most...

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PMID: 8817686
DOI: 10.1016/0955-2235(95)00026-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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