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Article

Transgenic mouse models for studying the functions of insulin-like growth factor-binding proteins.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Apr 2000

Schneider M R, Lahm H, Wu M, Hoeflich A, Wolf E

Abstract excerpt

The insulin-like growth factor-binding proteins (IGFBPs) comprise a family of six related peptides that interact with high affinity with IGFs. IGFBPs compete with IGF receptors for IGF binding, and as a consequence of this competition they can affect cell growth. In addition, IGF-independent regulatory mechanisms of IGFBPs have been described. Despite their common property to interact with IGFs every IGFBP is...

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Source

Identifiers

PMID: 10744620
DOI: 10.1096/fasebj.14.5.629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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