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Article

Insulin-like growth factor binding protein (IGFBP-1) involvement in intrauterine growth retardation: study on IGFBP-1 overexpressing transgenic mice.

Endocrinology - 1 Oct 2006

Ben Lagha Nadia, Seurin Danielle, Le Bouc Yves, Binoux Michel, Berdal Ariane, Menuelle Pierrette, Babajko Sylvie

Abstract excerpt

In humans, intrauterine growth retardation is correlated to high levels of serum IGF binding protein-1 (IGFBP-1). This present study analyzes in vivo the impact of circulating IGFBP-1 on body growth associated to bone mineralization and carbohydrate resources. Transgenic mice used in this work overexpressed human IGFBP-1 in liver from embryonic day (E)14.5, concomitantly to the appearance of ossification centers,...

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Identifiers

PMID: 16809446
DOI: 10.1210/en.2006-0171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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