Article
Rate of development of mutation at codon 215 of HIV-1 reverse transcriptase and its predictive factors at the time of initiation of zidovudine therapy.
European journal of clinical investigation - 1 Jun 1996
Leal M, Rey C, Torres Y, Relimpio F, Pino R, Lissen E, Sánchez-Quijano A, Luque F
Abstract excerpt
The objective of the present study was to determine the rate of development of mutation at codon 215 of HIV-1 reverse transcriptase and to identify baseline characteristics associated with this mutation following initiation of zidovudine therapy. To achieve such a purpose, 80 HIV-1-infected patients starting zidovudine therapy have been submitted to clinical, immunological and virological monitoring at entry and...
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