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Article

Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons

6 Nov 2001

Abstract excerpt

Transmission of HIV-1 with reduced susceptibility to antiretroviral drugs raises public health concerns. Through surveillance of drug-resistant HIV-1 in 603 treatment-naive, recently diagnosed HIV-1-infected persons, we identified a distinct group of viruses that have mutations at codon 215 of the reverse transcriptase (RT) gene that are different from either the wild-type (WT) T or the zidovudine (AZT)-selected...

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Identifiers

PMID: 11698656
DOI: 10.1073/pnas.241300698

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