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Article

Occurrence of HIV-1 reverse transcriptase gene mutation at codon 215 in HIV-infected infants.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Aug 2001

Kamkamidze G, Sullivan T, Charbonneau T

Abstract excerpt

BACKGROUND: The nucleoside reverse transcriptase inhibitor Zidovudine (ZDV) decreases mother to child transmission of HIV infection. Nevertheless, significant proportions of mothers who are treated during pregnancy with ZDV still transmit the virus. Along with other factors, failure of ZDV prophylaxis may be due to maternal infection with ZDV-resistant strains and their consequent vertical transmission....

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Identifiers

PMID: 11418362
DOI: 10.1016/s1386-6532(01)00178-0

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