Article
Phenotyping and genotyping of coagulation factor V Leiden.
Thrombosis and haemostasis - 1 Feb 1996
Engel H, Zwang L, van Vliet H H, Michiels J J, Stibbe J, Lindemans J
Abstract excerpt
The currently used activated Protein C resistance test demonstrated to be of limited diagnostic value for the detection of the mutant Factor V Leiden. Moreover, this assay is not useful for patients under anticoagulant therapy. A modification of the APC resistance test, applying Factor V deficien...
Topics
- Base Sequence
- DNA Mutational Analysis
- Disease Susceptibility
- Factor V
- Factor V Deficiency
- Genotype
- Humans
- Molecular Sequence Data
- Phenotype
- Point Mutation
- Polymerase Chain Reaction
- Thrombophlebitis