Article
Effect of angiotensin-converting enzyme genotype on renin-angiotensin components in hypertensives.
Clinica chimica acta; international journal of clinical chemistry - 15 Aug 1996
Zee R Y, Schrader A P, Morris B J
Abstract excerpt
Plasma angiotensin-converting enzyme (ACE) tracks with the deletion allele of an insertion/deletion (I/D) polymorphism of the ACE gene. The aim of the present study was to determine plasma renin and angiotensinogen for each ACE genotype in 54 hypertensive and 96 normotensive subjects. Plasma renin was reduced by 52 +/- 15 S.E.% in DD and by 24 +/- 12% in ID hypertensives when compared to II hypertensives (P <...
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