Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Significance of genetic polymorphisms of the renin-angiotensin-aldosterone system in cardiovascular and renal disease.

Pharmacogenomics - 1 Mar 2009

Rudnicki Michael, Mayer Gert

Abstract excerpt

The angiotensin converting enzyme (ACE) is a component of the renin-angiotensin-aldosterone system (RAAS). The RAAS--involved primarily in blood pressure and sodium homeostasis--is activated in many renal and cardiovascular diseases, and therapy with ACE inhibitors and other blockers of the RAAS has proven to be clinically beneficial. Plasma and tissue levels of ACE are at least partially determined by a genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme Inhibitors
Share to Carrier State

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Diabetic Nephropathies

Share to Kidney Diseases

Share to Kidney Failure, Chronic

Share to Peptidyl-Dipeptidase A

Share to Renin-Angiotensin System

Source

Identifiers

PMID: 19290794
DOI: 10.2217/14622416.10.3.463

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Significance of genetic polymorphisms of the renin-angiotensin-aldosterone system in cardiovascular and renal disease.PMID 19290794Read ↗

ACE insertion/deletion polymorphism and diabetic nephropathy: clinical implications of genetic information.Semantic proximity Read ↗

<i>ACE</i> PolymorphismsSemantic proximity Read ↗

ACE genotype and ACE inhibitor response in kidney disease: a perspective.Semantic proximity Read ↗

[Gene polymorphisms of renin-angiotensin-aldosterone system components and the progression of chronic kidney diseases].Semantic proximity Read ↗

Pharmacogenomics of angiotensin converting enzyme inhibitors in renal disease--pathophysiological considerations.Semantic proximity Read ↗

Angiotensin-converting enzyme gene I/D polymorphism and renal disease.Semantic proximity Read ↗

Angiotensin converting enzyme gene polymorphisms and renal disease.Semantic proximity Read ↗

Genetic polymorphisms in the renin–angiotensin system: relevance for susceptibility to cardiovascular diseaseSemantic proximity Read ↗

[The renin-angiotensin system as the basic principle for hypertension and coronary heart diseases--role of genetic factors].Semantic proximity Read ↗

Genetic variability in the renin-angiotensin system: prevalence of alleles and genotypes.Semantic proximity Read ↗

Angiotensin converting enzyme insertion/deletion polymorphism and renoprotection in diabetic and nondiabetic nephropathies.Semantic proximity Read ↗

Interaction Between Genetic Polymorphisms in Renin-Angiotensin System (RAS) and Therapeutic Efficacy of RAS Blockade in IgA Nephropathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.