Article
Genetic variability in the renin-angiotensin system: prevalence of alleles and genotypes.
Journal of cardiovascular risk - 1 Jan 2000
Staessen J A, Ginocchio G, Wang J G, Saavedra A P, Soubrier F, Vlietinck R, Fagard R
Abstract excerpt
BACKGROUND: Variants of the human genes coding for renin, angiotensin-converting enzyme (ACE), angiotensinogen (AGT) and the angiotensin II type-I receptor (AT1R) are inconsistently associated with cardiovascular-renal disease, possibly because of genetic differences in the background populations. METHODS: This systematic review of the literature investigated genetic variation in the renin system according to...
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