Allelotype of pancreatic adenocarcinoma using xenograft enrichment.

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Article

Allelotype of pancreatic adenocarcinoma using xenograft enrichment.

Cancer research - 15 Oct 1995

Hahn S A, Seymour A B, Hoque A T, Schutte M, da Costa L T, Redston M S, Caldas C, Weinstein C L, Fischer A, Yeo C J

Abstract excerpt

p53 and MTS1 are known to be mutationally inactivated in pancreatic adenocarcinoma. Other tumor suppressor genes are likely also to play a role. To define chromosomal arms which may harbor additional tumor suppressor genes, we performed an extensive allelotype on pancreatic cancer utilizing a xen...

Topics

Adenocarcinoma
Alleles
Animals
Carrier Proteins
Chromosome Mapping
Cyclin-Dependent Kinase Inhibitor p16
DNA, Neoplasm
Genes, Tumor Suppressor
Heterozygote
Mice
Mice, Nude
Neoplasm Transplantation
Pancreatic Neoplasms
Point Mutation
Sequence Deletion
Transplantation, Heterologous

Source

Open in PubMed

Identifiers

PMID: 7553647

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7553647-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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