Article
Allelotype of pancreatic adenocarcinoma.
Cancer research - 15 May 1994
Seymour A B, Hruban R H, Redston M, Caldas C, Powell S M, Kinzler K W, Yeo C J, Kern S E
Abstract excerpt
Knowledge of the patterns of allelic loss has been useful in identifying the spectrum of the tumor suppressor genes involved in various tumor types. Such analyses in pancreatic carcinoma have been difficult due to the characteristic host desmoplastic reaction to the neoplasm. We have assembled the first allelotype of pancreatic adenocarcinoma, a survey for allelic loss among each chromosomal arm, using seven...
Topics
- Adenocarcinoma
- Alleles
- Gene Deletion
- Genotype
- Humans
- Pancreatic Neoplasms