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Article

Selective expression of one c-myc allele in two human myeloma cell lines.

Cancer research - 1 Oct 1996

Kuehl W M, Brents L A, Chesi M, Bergsagel P L

Abstract excerpt

Chromosomal translocations or DNA rearrangements affecting c-myc occur in almost all murine plasmacytoma and human Burkitt's lymphoma tumors and are associated with a high incidence of exon 2 missense mutations and selective expression of the affected allele. Screening nine multiple myeloma cell lines, we identified no exon 2 missense mutations but did identify two lines with single, silent mutations in exon 1...

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PMID: 8813127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Selective expression of one c-myc allele in two human myeloma cell lines.PMID 8813127Read ↗

Dysregulation of c-myc in multiple myeloma.Semantic proximity Read ↗

Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas.Semantic proximity Read ↗

Mutations in the coding region of c-myc occur independently of mutations in the regulatory regions and are predominantly associated with myc/Ig translocation.Semantic proximity Read ↗

Novel targeted deregulation of c-Myc cooperates with Bcl-XL to cause plasma cell neoplasms in miceSemantic proximity Read ↗

Nucleotide sequence comparison of normal and translocated murine c-myc genes.Semantic proximity Read ↗

Allele-specific activation of the c-myc gene in an atypical Burkitt's lymphoma carrying the t(2;8) chromosomal translocation 250 kb downstream from c-myc.Semantic proximity Read ↗

Expression of the bcl-2 gene in human multiple myeloma cell lines and normal plasma cellsSemantic proximity Read ↗

The c-MYC allele that is translocated into the IgH locus undergoes constitutive hypermutation in a Burkitt's lymphoma line.Semantic proximity Read ↗

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